Mammalian Cytochrome P450-Dependent Metabolism of Polychlorinated Dibenzo-p-dioxins and Coplanar Polychlorinated Biphenyls

Mammalian Cytochrome P450-Dependent Metabolism of Polychlorinated Dibenzo-p-dioxins and Coplanar Polychlorinated Biphenyls

Polychlorinated dibenzo-p-dioxins (PCDDs) and coplanar polychlorinated biphenyls (PCBs) contribute to dioxin toxicity in humans and wildlife after bioaccumulation through the food chain from the environment. The authors examined human and rat cytochrome P450 (CYP)-dependent metabolism of PCDDs and PCBs. A number of human CYP isoforms belonging to the CYP1 and CYP2 families showed remarkable act...

Polychlorinated biphenyls, polybrominated biphenyls, polychlorinated dibenzo-p-dioxins, and polychlorinated dibenzofurans

This chapter was originally published in the book Veterinary Toxicology, published by Elsevier, and the attached copy is provided by Elsevier for the author’s benefit and for the benefit of the author’s institution, for non-commercial research and educational use including without limitation use in instruction at your institution, sending it to specific colleagues who know you, and providing a ...

Polychlorinated dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs) and biphenyls (PCBs)

Atmospheric Bulk Deposition of Polychlorinated Dibenzo-p-Dioxins, Dibenzofurans, and Polychlorinated Biphenyls in Finland

The deposition of polychlorinated dibenzo-p-dioxins, dibenzofurans (PCDD/Fs), and polychlorinated biphenyls (PCBs) was studied during the period 2006–2008 in northern Finland (Pallas), 1998–2008 in southern Finland (Evo) and 2002–2004 in the Gulf of Finland archipelago (Utö). Retrospective snow samples were taken from the whole snowbank in Evo in 2003 and 2004, and recently fallen snow was coll...

Polychlorinated dibenzo-p-dioxins and dibenzofurans and polychlorinated biphenyls in surface soil from the Tibetan Plateau.

Concentrations of Polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and polychlorinated biphenyls (PCBs) in soil samples from Tibetan Plateau were determined. The average concentration of total 2,3,7,8-PCDD/Fs was (2.30±1.02) pg/g, and World Health Organization Toxicity Equivalency (WHO-TEQ) average concentration was (0.013±0.010) pgWHO-TEQ/g. The average concentration of ∑PCBs (7 i...